In this paper, artificial meta-molecules are assembled using DNA origami arranging metallic nano-spheres. The CD signals of experiment and theory are in good agreement. A sign flip of the CD can be achieved for the addition or removal of single particles within the molecules.
K. Martens, et al. Onset of Chirality in Plasmonic Meta-Molecules and Dielectric Coupling. ACS Nano, 16, 16143-16149, (2022).